High carbapenem use in targeting non-severe ECR Enterobacterales infections in US hospitals predates 2020 IDSA guidance and has persisted thereafter. Efforts to increase awareness and implementation of recommendations among clinicians to use carbapenem...
Participants who had tetravalent dengue purified inactivated vaccine prime and live-attenuated vaccine boost were unprotected against dengue virus-1 infection and further showed increased clinical, immunological, and transcriptomic evidence for inflamm...
Dengue is an acute mosquito-borne illness that is caused by four different dengue viruses (serotypes 1–4). More than half the world's population lives at risk of dengue. Among the different approaches being explored to prevent dengue, an effective vacc...
The incidence of extended-spectrum β-lactamase-producing Enterobacterales infections has increased substantially in recent years, now accounting for approximately 15% of isolates causing infections.1 Understanding the management of these infections is ...
SARS-CoV-2 viral clearance kinetics in symptomatic, vaccinated individuals accelerated substantially over 2 years of the pandemic, necessitating a change to how new SARS-CoV-2 antivirals are compared (ie, shortening the period of pharmacodynamic assess...
With almost 775 million COVID-19 cases reported worldwide and 67% of the global population vaccinated with a complete primary series of a COVID-19 vaccine, the deadly pace of the pandemic has slowed down substantially.1 Sculpted by infection, immunisat...
Mass gatherings can attract several million people from across the world and pose huge public health challenges for the host country.1 The Hajj is one of the world's largest annual religious events, in which up to 4 million pilgrims from 182 countries ...
Mass gatherings can attract several million people from across the world and pose huge public health challenges for the host country.1 The Hajj is one of the world's largest annual religious events, in which up to 4 million pilgrims from 182 countries ...
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms. Further research is needed to verify a mechanisti...
In their study in The Lancet Infectious Diseases, Wenting Zuo and colleagues collected tissue samples from 225 patients who had recovered from mild COVID-19 and found that SARS-CoV-2 viral RNA was distributed across ten distinct solid tissues, plasma, ...
Czech Republic is experiencing the largest outbreak of pertussis in more than 60 years, with suboptimal vaccine coverage and waning immunity partly to blame. Ed Holt reports.
In response to the UN's seventeen SDG agenda for 2030, which fosters research focused on global targets addressing some of society's biggest challenges, an accompanying body of work, a SDG programme, has been launched by Springer Nature. The programme ...
In a month when France has enshrined abortion as a constitutional legal right and the state of Arizona, USA, has voted to reinstate a law banning all abortions from conception unless it is necessary to save the life of the pregnant person, it is easy t...
Recognition of misinformation as a public health threat and interest in infodemics, defined as an inundation of information accompanying an epidemic or acute health event, have increased worldwide. However, scientists have no consensus on how to best d...
Recognition of misinformation as a public health threat and interest in infodemics, defined as an inundation of information accompanying an epidemic or acute health event, have increased worldwide. However, scientists have no consensus on how to best d...
Our detailed breakdown of DALYs associated with a comprehensive list of pathogens on a global, regional, and country level has revealed the magnitude of the problem and helps to indicate where research funding mismatch might exist. Given the disproport...
