[Articles] Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis

Di |2022-07-02T00:30:01+02:00Luglio 2nd, 2022|Categorie: Coronavirus Lancet|

Autochthonous community monkeypox virus transmission is currently observed among MSM in the UK. We found a high proportion of concomitant STIs and frequent anogenital symptoms, suggesting transmissibility through local inoculation during close skin-to-...

[Corrections] Correction to Lancet Infect Dis 2022; published online June 21. https://doi.org/10.1016/S1473-3099(22)00234-1

Di |2022-06-30T00:30:01+02:00Giugno 30th, 2022|Categorie: Coronavirus Lancet|

Mashau RC, Meiring ST, Quan VC, et al. Outcomes of flucytosine-containing combination treatment for cryptococcal meningitis in a South African national access programme: a cross-sectional observational study. Lancet Infect Dis 2022; published online Ju...

[Articles] Safety and immunogenicity of VPM1002 versus BCG in South African newborn babies: a randomised, phase 2 non-inferiority double-blind controlled trial

Di |2022-06-28T00:30:02+02:00Giugno 28th, 2022|Categorie: Coronavirus Lancet|

VPM1002 was less reactogenic than BCG and was not associated with any serious safety concern. Both vaccines were immunogenic, although responses were higher with the BCG vaccine. VPM1002 is currently being studied for efficacy and safety in a multicent...

[Articles] Immunogenicity, otitis media, hearing impairment, and nasopharyngeal carriage 6-months after 13-valent or ten-valent booster pneumococcal conjugate vaccines, stratified by mixed priming schedules: PREVIX_COMBO and PREVIX_BOOST randomised controlled trials

Di |2022-06-28T00:30:01+02:00Giugno 28th, 2022|Categorie: Coronavirus Lancet|

Low antibody concentrations 6 months post-booster might indicate increased risk of pneumococcal infection. The preferred booster was PCV13 if priming did not have PCV13, otherwise either PCV13 or PHiD-CV10 boosters provided similar immunogenicity. Mixe...

[Articles] Efficacy of RTS,S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial

Di |2022-06-24T00:30:02+02:00Giugno 24th, 2022|Categorie: Coronavirus Lancet|

The Fx012-14 regimen was not superior to the standard regimen over 12 months after dose three. All RTS,S/AS01E regimens provided substantial, similar protection against clinical malaria, suggesting potential flexibility in the recommended dosing regime...

[Comment] Adding to the mantra: vaccines prevent illness and death, and preserve existing antibiotics

Di |2022-06-24T00:30:02+02:00Giugno 24th, 2022|Categorie: Coronavirus Lancet|

With rising incomes and the increased availability of antibiotics globally, per-capita consumption of antibiotics in middle-income countries is fast approaching the rates in high-income countries.1 Antimicrobial resistance has emerged as a major source...