Tuberculosis remains a formidable global health challenge, causing substantial morbidity and mortality due to the limited protection in the lungs provided by the current BCG vaccine.1 The urgent need for an effective tuberculosis vaccine has prompted i...
A vaccine against chlamydia is widely agreed to be an essential public health control measure for both sexually transmitted and ocular infections.1 There have been many decades and much investment in research towards a chlamydial vaccine, and it has be...
CTH522, adjuvanted with CAF01 or CAF09b, is safe and immunogenic, with 85 μg CTH522-CAF01 inducing robust serum IgG binding titres. Intradermal vaccination conferred systemic IgG neutralisation breadth, and topical ocular administration increased ocula...
The three dose groups of the candidate v7D vaccine exhibit similar humoral immunogenicity to the vOka vaccine and are well tolerated. These findings encourage further investigations on two-dose vaccination schedules, efficacy, and the potential safety ...
Varicella, also known as chickenpox, is an infectious disease with a characteristic skin rash caused by the Varicella zoster virus. After the initial infection, varicella zoster virus can remain dormant and potentially reactivate in later life as herpe...
Despite the non-specific and mild presentation of L monocytogenes-associated spontaneous bacterial peritonitis, the outcome is poor and similar to that of neurolisteriosis, and so identification of L monocytogenes in ascitic fluid samples requires urge...
Despite the non-specific and mild presentation of L monocytogenes-associated spontaneous bacterial peritonitis, the outcome is poor and similar to that of neurolisteriosis, and so identification of L monocytogenes in ascitic fluid samples requires urge...
Despite the non-specific and mild presentation of L monocytogenes-associated spontaneous bacterial peritonitis, the outcome is poor and similar to that of neurolisteriosis, and so identification of L monocytogenes in ascitic fluid samples requires urge...
Invasive listeriosis is one of the most serious foodborne diseases, and can be categorised into three main clinical forms: septicaemic listeriosis, neurolisteriosis, and pregnancy-associated listeriosis.1 Listeria monocytogenes-associated spontaneous b...
Invasive listeriosis is one of the most serious foodborne diseases, and can be categorised into three main clinical forms: septicaemic listeriosis, neurolisteriosis, and pregnancy-associated listeriosis.1 Listeria monocytogenes-associated spontaneous b...
Invasive listeriosis is one of the most serious foodborne diseases, and can be categorised into three main clinical forms: septicaemic listeriosis, neurolisteriosis, and pregnancy-associated listeriosis.1 Listeria monocytogenes-associated spontaneous b...
“All happy families are alike; each unhappy family is unhappy in its own way” is the famous opening of Lev Tolstoj's masterpiece Anna Karenina. And among unhappy families immortalised in literature, the Tyrone family, at the centre of American playwrig...
Persistent symptoms among some individuals who develop COVID-19 have led to the hypothesis that SARS-CoV-2 might, in some form or location, persist for long periods following acute infection.1,2 Studies on SARS-CoV-2 persistence to date, however, have ...
Orthohantaviruses belong to emerging zoonotic pathogens of global public health importance that can cause occasional outbreaks, often associated with conflict.1–3 These viruses are also categorised as category C pathogens by the US Centers for Disease ...
ANDV infection is a systemic and viraemic infection, that affects various organs. The presence of infectious particles in body fluids contributes to our understanding of potential mechanisms for person-to-person transmission, supporting the development...
We thank Duffy and colleagues1 for highlighting the importance of zoonotic tuberculosis. The Quadripartite, formed by the Food and Agriculture Organization of the UN (FAO), the UN Environment Programme, the World Organisation for Animal Health (WOAH), ...
