In their open-label extension of the doxycycline post-exposure prophylaxis (doxy-PEP) randomised controlled trial (RCT), Anne F Luetkemeyer and colleagues1 conclude that doxy-PEP did not select for gonococcal antimicrobial resistance. Although the use ...
We share Vanbaelen and colleagues' interest in understanding evolving gonococcal antimicrobial resistance and potential association with doxycycline prophylaxis for prevention of sexually transmitted infections, which we studied as doxycycline post-exp...
Lactational mastitis is a common condition during breastfeeding, which, in rare cases, can progress to life-threatening necrotising mastitis, particularly in cases where Streptococcus pyogenes is involved. The development of streptococcal toxic shock s...
As the Trump administration lays off staff and cuts public health funding, experts warn they risk undoing decades of progress in infectious disease control. Vijay Shankar Balakrishnan reports.
We read with great interest the recent Editorial published in The Lancet Infectious Diseases,1 which forcefully calls attention to the troubling global resurgence of measles, a long-preventable disease that is now tragically making a comeback. The Edit...
Antimicrobial resistance is considered one of the main challenges to health at the global level. In 2024, WHO updated its list of bacterial priority pathogens, whose update is detailed in an Article published in this journal) and one bacterium highligh...
The 2024 WHO BPPL is a key tool for prioritising research and development investments and informing global public health policies to combat AMR. Gram-negative bacteria and rifampicin-resistant M tuberculosis remain critical priority pathogens, undersco...
Antimicrobial resistance (AMR) in bacteria commonly implicated in hospital-associated and some community-associated infections is a major public health threat, with 1·91 million deaths attributable to AMR bacterial infections projected in 2050, most of...
Since October, 2023, Oropouche virus (OROV) has caused a large outbreak of Oropouche fever in the Americas, exposing yet again the vulnerabilities of infectious disease surveillance systems. These weaknesses are far from a uniquely Latin American probl...
Our data suggest that climatic factors are major drivers of OROV spread and were potentially exacerbated during 2024 by extreme weather events. OROV glycoprotein reassortants, but not individual OROV strains, probably have distinct antigenicity. Prepar...
Growing up in Vienna, Austria, Michael Ramharter recalls discussing human biology with his dentist father. He thinks these talks influenced his interest in health sciences. But he notes, “I was very sure from very early age that he did not want to beco...
Raised in southern Austria, Elisabeth Presterl originally wanted to be an archaeologist, following in the footsteps of her academically accomplished family. “My mother had a doctorate in philosophy and was a schoolteacher, my father was an electrical e...
Cornelia Lass-Flörl had originally wanted to be an anaesthesiologist and intensive care medicine specialist, believing that's where the action was. But after her medical studies at the University of Innsbruck and working in ICU at Kufstein Hospital, La...
Sepsis is a leading cause of preventable death and requires timely antimicrobial treatment to reduce mortality. Despite extensive sepsis management guidelines, high-income countries continue to have considerable rates of sepsis mortality, indicating a ...
As a document leaked to the press indicates that Gavi will lose financial backing from the USA, we ask what this could mean for the future of the programme. Talha Burki reports.
We commend the Correspondence from Hailie Uren and colleagues, who described the first substantial volume clinical antimicrobial susceptibility testing data set in Ukraine in recent years.1 The volume of data substantially broadens regional situational...