CONCLUSION: Emphasizing the well-being of the nurses caring for critical COVID-19 patients during the pandemic is necessary to enable them to provide high-quality nursing care.
COVID-19 has led to unprecedented health and social measures in several countries, including major restrictions on funeral rituals. These restrictions concerned pre-mortem, peri-mortem and post-mortem rites. Based on a longitudinal study of 955 French-speaking Canadians bereaved of a loved one during the pandemic, this article describes the reality of these impediments. Through an analysis of the quantitative and qualitative data collected, it is possible to identify the gap between desired and...
The U.S. public health response to coronavirus disease 2019 (COVID-19) has been widely criticized as having downplayed the potential implications COVID-19 could have on one's personal health. Despite the unprecedented threat of COVID-19, many individuals still believed that it was not at all likely that they would become infected. We sought to investigate trends in adults' perceived susceptibility to COVID-19 over the first year of the pandemic, whether distinct trajectories emerged, and if...
Boston-based Moderna is one of the key players in mRNA vaccines, and has, with mRNA1273 (Spikevax®) developed and approved, one of the two mRNA based COVID 19 vaccines on the market. Recently, a patent application was published which Moderna filed in early 2020, and which protects Spikevax. This article explains legal issues and disputes that are involved with this patent application.
COVID-19 patients with cardiovascular diseases who are at higher risk of progressing to critical illness should be treated with Paxlovid. Ritonavir, the booster in Paxlovid, modulates multiple drug metabolizing enzymes and transporters, complicating its use in real-world clinics. We aimed to apply physiologically based pharmacokinetic (PBPK) modelling to simulate the complex drug-drug interactions (DDIs) of ritonavir with two anticoagulants, rivaroxaban and racemic warfarin, to address this...
CONCLUSION: Participants benefited from the concept and rapid implementation of a live video-conference-based seminar on "Hygiene under Pandemic Conditions". The positive experience in terms of guidance, advice and training provides the basis for implementing a dedicated "Hygiene" module in Kosovo.
The COVID-19 pandemic has changed lives in an unprecedented way. The most notable and urgent requirement to combat the epidemic was to transform the way human interacts with each other. The adherence to maintaining social distance has given an upsurge to the increased usage of mobile app users. This change in human interaction for fulling their basic to social to work needs through the intervention of app usage has led to privacy concerns by users. By keeping in view the changing dynamics of the...
During fall 2020 in rural Pierce County, Washington, school districts and the county health department offered weekly rapid antigen screening to students and staff. Asymptomatic screening identified 42.5% of confirmed cases from the population. Parents reported it was a positive experience for their children. The program supported decisions to return to in-person learning, but screening ended because of resource and technical limitations. When planning in-school screening, stakeholder engagement...
CONCLUSION: Although COVID-19 associated pediatric vasculitis is very rare, awareness of this rare entity is important to secure earlier diagnosis and treatment. The clinical features of COVID-19 associated pediatric vasculitis subtypes look similar to those in pediatric vasculitis not associated with COVID-19. Whether COVID-19 is the reason of the vasculitis or only the trigger remains unknown.
CONCLUSIONS: Post-COVID, different forms of HTA must be embraced as part of the new HTA landscape in addition to increased intra- and intercountry collaboration across all sectors of the health system, including regulatory bodies.
CONCLUSIONS: Mental health care utilisation rates for inpatient and outpatient services decreased substantially after the introduction of the lockdown. Hospital admissions and outpatient consultations for alcohol withdrawal syndrome increased after the introduction of the lockdown, but statistical uncertainty precludes strong conclusions about a potential unintended effect of the alcohol sales ban. Governments should integrate strategies for ensuring access and continuity of essential mental...
Among numerous SARS-CoV-2 VOCs, Omicron is more infectious and immune-escaping, while Delta is more pathogenic. Here, we provide evidence for both inter-variant and intra-variant recombination of the rapidly evolving new SARS-CoV-2 strains, including XD/XE/XF and BA.3, raising concerns of potential more infectious, immune-escaping, and disease-causing Omicron and Delta-Omicron variants. This article is protected by copyright. All rights reserved.
CONCLUSION: The COVID-19 pandemic was associated with an improvement in the bystander CPR rate in Tokyo, while patient outcomes were maintained. Pandemic-related changes in patient and bystander characteristics do not fully explain the underlying mechanism; there may be other mechanisms through which the community response to public emergency increased during the pandemic.
CONCLUSION: Levels of anxiety and self-isolation decreased after the initial lock-down period in patients with IRD. Half of patients reported self-isolation in May 2021, -a phase with wide-spread re-opening of society and large-scale vaccination. Lack of pre-pandemic data prevented a full understanding of the long-term impact of the pandemic on anxiety and self-isolation in IRDs.
Public health and social measures (PHSM) have been central to the COVID-19 response. Consequently, there has been much pressure on decision-makers to make evidence-informed decisions and on researchers to synthesize the evidence regarding these measures. This article describes our experiences, responses and lessons learnt regarding key challenges when planning and conducting rapid reviews of PHSM during the COVID-19 pandemic. Stakeholder consultations and scoping reviews to obtain an overview of...
CONCLUSIONS: Our results show that our theatre start times were better during the COVID-19 pandemic and overall theatre efficiency was maintained despite the additional COVID-19 infection control protocols that were in place. These findings suggest that well planned infection control protocols do not need to impede trauma theatre efficiency in certain settings.