A Hybrid Protocol for Identifying Comorbidity-Based Potential Drugs for COVID-19 Using Biomedical Literature Mining, Network Analysis, and Deep Learning

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has spread on an unprecedented scale around the globe. Despite of 141,975 published papers on COVID-19 and several hundreds of new studies carried out every day, this pandemic remains as a global challenge. Biomedical literature mining helps the researchers to understand the etiology of the disease and to gain an in-depth knowledge of the disease, potential drugs, vaccines developed and...

Development of a training programme for professional nurses in South Africa – An educational response to the COVID-19 pandemic

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

CONCLUSION: The training programme aimed to enhance the knowledge of professional nurses in the management of critically ill patients with COVID-19. As the pandemic evolves, a need for training and ongoing support was identified, which might address the need for surge capacity and hospital readiness planning.

The adoption of socially assistive robots for long-term care: During COVID-19 and in a post-pandemic society

Di |2022-06-17T13:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

The rapid spread of COVID-19 has prompted a surge in the adoption of technology, highlighting a number of potential applications for Socially Assistive Robots (SARs). Our entire healthcare system has been under unprecedented strain, and going forward, we must consider how robotic technology could help improve the quality of care and day-to-day functionality of our care facilities. Herein, we present our human-robot interaction study in a local long-term care centre during the pandemic and the...

Mechanism of Multi-Organ Injury in Experimental COVID-19 and Its Inhibition by a Small Molecule Peptide

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

Severe disease from SARS-CoV-2 infection often progresses to multi-organ failure and results in an increased mortality rate amongst these patients. However, underlying mechanisms of SARS- CoV-2-induced multi-organ failure and subsequent death are still largely unknown. Cytokine storm, increased levels of inflammatory mediators, endothelial dysfunction, coagulation abnormalities, and infiltration of inflammatory cells into the organs contribute to the pathogenesis of COVID-19. One potential...

The Impact of the COVID-19 Pandemic on Food Insecurity in Northern New England Primary and Prenatal Care Settings

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

CONCLUSION: Results suggest that practices and surrounding communities in northern New England responded to FI during the pandemic by increasing food support programs. Future work is needed to examine the impact of food programs initiated during the pandemic and determine optimal strategies for practices to address FI among patients.

Mask-associated dry-eye in COVID-19 pandemic: A case report and review of the literature

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

Mask-Associated Dry Eye (MADE) has been showing a rising trend during COVID 19 pandemic. This phenomenon seems inevitable, as wearing a face mask is a requisite part of personal protective measures to suppress of the spread of virus. However, simple expeditious awareness among health care staff, including the general population, can decrease the incidence.

Targeting Virus-Induced Reprogrammed Cell Metabolism via Glycolytic Inhibitors: An Effective Therapeutic Approach Against SARS-CoV-2

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

Reprogrammed cell metabolism has been observed in a wide range of viral infected cells. Viruses do not have their metabolism; they rely on the cellular metabolism of the host to ensure the energy and macromolecules requirement for replication. Like other viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) does not own its metabolism, but viral infected cells adopt aberrant cell metabolism. Infected viral cells, uses the energy and macromolecules to make their own copies, to do...

Quantifying the Risk to Health Care Workers of Cough as an Aerosol Generating Event in an Ambulance Setting: A Research Report

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

CONCLUSION: Further research is required to provide clarity of the risk to health care workers when caring for a coughing patient in the confined clinical ambulance setting and to provide an evidence base to assist in the determination of appropriate respiratory protective equipment (RPE).

Hesitancy of COVID-19 vaccines: Rapid systematic review of the measurement, predictors, and preventive strategies

Di |2022-06-17T13:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

Vaccine hesitancy is one of the top ten global health threats and the first threat to fighting COVID-19 through vaccination. With the increasing level of COVID-19 vaccine hesitancy amidst the rising level of confirmed cases and death tolls, this paper provides rapid systematic literature reviews on the measurement of COVID-19 vaccine hesitancy, key determinants and evidence-based strategies to prevent COVID-19 vaccine hesitancy. The findings reveal three standard measures of vaccine hesitancy:...

The fading impact of lockdowns: A data analysis of the effectiveness of Covid-19 travel restrictions during different pandemic phases

Di |2022-06-17T13:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

As countries struggled with SARS-COV2 outbreaks at the beginning of 2021, many citizens found themselves in yet another period of increasing travel restrictions, if not a strict lockdown. At the same time there was concern that further restrictions would prove to be less effective due to a range of reasons including increasing pandemic fatigue or the lack of appropriate supports. In this study we investigate whether restrictions remained effective as a way to limit non-essential travel in order...

Vaccination and modern management of chronic obstructive pulmonary disease – a narrative review

Di |2022-06-17T13:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) carries a tremendous societal and individual burden posing significant challenges for public health systems worldwide due to its high morbidity and mortality. Due to aging, multimorbidity but also in the wake of important progress in deciphering the heterogeneous disease endotypes, an individualized approach to the prevention and management of COPD is necessary.

Uptake of long-acting reversible contraception after telemedicine delivered abortion during Covid-19

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

CONCLUSION: During COVID-19 there was demand for post-abortion LARC but less than half of patients received this by six weeks. Provision was enhanced when in-person clinical interactions took place. Interventions are required to facilitate timely access and initiation of LARC with telemedicine delivered abortion care.

Can a new ward environment and intensive allied health staffing model enhance therapeutic opportunities in trauma care? A behavioural mapping study of patients’ activities and interactions

Di |2022-06-17T00:00:00+02:00Giugno 17th, 2022|Categorie: Coronavirus PubMed|

CONCLUSIONS: Greater engagement in physical and social activities was observed following the implementation of the new allied health staffing model at a level 1 trauma centre. Whether these changes translate to improved trauma outcomes is important to investigate.

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