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Heparin-binding protein levels predict unfavorable outcome in COVID-19 pneumonia: A post-hoc analysis of the SAVE trial

Di |2024-03-22T16:00:00+01:00Marzo 22nd, 2024|Categorie: Coronavirus PubMed|

We aimed to evaluate heparin-binding protein (HBP) as a marker of prognosis of unfavorable outcome in COVID-19 pneumonia. This was a post-hoc analysis of the SAVE clinical trial investigating anakinra treatment, guided by suPAR (soluble urokinase plasminogen activator receptor) levels ≥6 ng/ml, for the prevention of severe respiratory failure (SRF) in hospitalized patients with COVID-19 pneumonia. Baseline HBP plasma levels were measured in 534 patients by fluorescence dry quantitative...

Moral Stress and Moral Distress: Confronting Challenges in Healthcare Systems under Pressure

Di |2023-06-22T03:00:00+02:00Giugno 22nd, 2023|Categorie: Coronavirus PubMed|

Stresses on healthcare systems and moral distress among clinicians are urgent, intertwined bioethical problems in contemporary healthcare. Yet conceptualizations of moral distress in bioethical inquiry often overlook a range of routine threats to professional integrity in healthcare work. Using examples from our research on frontline physicians working during the COVID-19 pandemic, this article clarifies conceptual distinctions between moral distress, moral injury, and moral stress and...

Cutaneous Adverse Events Following 771 Doses of the Inactivated and mRNA Covid-19 Vaccines: a Survey Study Among Health Care Providers

Di |2022-07-01T06:00:00+02:00Luglio 1st, 2022|Categorie: Coronavirus PubMed|

INTRODUCTION: As Coronavirus disease 19 (Covid-19) still continues to affect humanity worldwide, different types of Covid-19 vaccines are being administered to maintain immunization against Covid-19. As both the inactivated and mRNA vaccines are now being applied prevalently, systemic adverse events along with cutaneous side effects are frequently being reported in the literature.

Coronaviruses in wild animals sampled in and around Wuhan at the beginning of COVID-19 emergence

Di |2022-06-30T13:00:00+02:00Giugno 30th, 2022|Categorie: Coronavirus PubMed|

Over the last several decades, no emerging virus has had a profound impact on the world as the SARS-CoV-2 that emerged at the end of 2019 has done. To know where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated from and how it jumped into human population, we immediately started a surveillance investigation in wild mammals in and around Wuhan when we determined the agent. Herein, coronaviruses were screened in the lung, liver, and intestinal tissue samples from fifteen...

Relationship Between Optimism-Pessimism Levels of Mothers and Anxiety Levels of Children in Turkey During COVID-19 Pandemic

Di |2022-06-30T01:00:00+02:00Giugno 30th, 2022|Categorie: Coronavirus PubMed|

CONCLUSION: These findings suggest that mental health of children has been adversely affected during the pandemic and this has important implications for designing and implementing interventions aimed at reducing anxiety levels of children and determining protective and risk factors associated with anxiety in the face of adversity.

The nervous system during COVID-19: Caught in the crossfire<sup></sup>

Di |2022-06-30T01:00:00+02:00Giugno 30th, 2022|Categorie: Coronavirus PubMed|

SARS-CoV-2, the virus that causes coronavirus disease (COVID)-19, has become a persistent global health threat. Individuals who are symptomatic for COVID-19 frequently exhibit respiratory illness, which is often accompanied by neurological symptoms of anosmia and fatigue. Mounting clinical data also indicate that many COVID-19 patients display long-term neurological disorders postinfection such as cognitive decline, which emphasizes the need to further elucidate the effects of COVID-19 on the...

‘It was the worst possible timing’: the response of UK Longitudinal Integrated Clerkships to Covid-19

Di |2022-06-30T01:00:00+02:00Giugno 30th, 2022|Categorie: Coronavirus PubMed|

Covid-19 has altered medical education worldwide. Given recent events, UK Longitudinal Integrated Clerkships (LICs), which are relatively new innovations, may have changed in structure and delivery, or may have demonstrated resilience. Collating the responses and experiences of UK institutions may yield transferrable recommendations for institutions wishing to develop sustainable LICs. A mixed-methods survey concerning LIC prevalence, variety, and experiences of responses to Covid-19 was...

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