Nature Medicine, Published online: 24 January 2025; doi:10.1038/s41591-024-03486-6This proof-of-concept phase 1 trial shows that the size of circulating tumor cell clusters (which can promote metastatic spread) can be reduced by treatm...
Nature Medicine, Published online: 24 January 2025; doi:10.1038/s41591-025-03521-0Author Correction: Propagative α-synuclein seeds as serum biomarkers for synucleinopathies
Nature Medicine, Published online: 23 January 2025; doi:10.1038/s41591-024-03476-8This study systematically analyzed 175 health outcomes in 2 million people using glucagon-like peptide-1 receptor agonists (GLP-1RAs) or other antihyperg...
Nature Medicine, Published online: 23 January 2025; doi:10.1038/s41591-024-03436-2Brian J. Druker describes how his research on imatinib validated protein kinases as therapeutic targets for cancer and led to a life-saving treatment for...
Nature Medicine, Published online: 22 January 2025; doi:10.1038/s41591-024-03446-0Announced in this Comment and in collaboration with Nature Medicine is the convening of the Quality Health Information for All Commission, to promote equ...
Nature Medicine, Published online: 22 January 2025; doi:10.1038/s41591-024-03448-yAnnounced in this Comment and in collaboration with Nature Medicine is the convening of the Access to Dialysis in Low- and Middle-Income Countries Commis...
Nature Medicine, Published online: 22 January 2025; doi:10.1038/s41591-024-03464-yAs Nature Medicine celebrates its 30th anniversary, we reflect on the challenges ahead and what the future holds for medicine — and for our journal.
Nature Medicine, Published online: 22 January 2025; doi:10.1038/s41591-024-03450-4In a prespecified interim analysis of the randomized, double-blind phase 3 COMPASSION-15 trial, patients with advanced HER2-negative gastric/GEJ cancer t...
Nature Medicine, Published online: 21 January 2025; doi:10.1038/s41591-024-03415-7In this prespecified interim analysis of the KEYNOTE-756 phase 3 trial, pembrolizumab and chemotherapy treatment of patients with high-risk, early-stage,...
Nature Medicine, Published online: 21 January 2025; doi:10.1038/s41591-024-03414-8In the CheckMate 7FL trial, neoadjuvant nivolumab and chemotherapy in patients with newly diagnosed, high-risk estrogen receptor-positive breast cancer l...
Nature Medicine, Published online: 21 January 2025; doi:10.1038/s41591-024-03438-0Our Future Health has recruited more than 1 million participants in the UK, with biobanked bloods, making it the largest consented cohort of its type in ...
Nature Medicine, Published online: 21 January 2025; doi:10.1038/s41591-025-03504-1Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids
Nature Medicine, Published online: 20 January 2025; doi:10.1038/s41591-024-03434-4This Review explores the state-of-the-art applications of artificial intelligence in small-molecule drug development, from target identification and drug...
Nature Medicine, Published online: 20 January 2025; doi:10.1038/s41591-024-03478-6In an analysis of long-term safety events in 783 patients treated with T cell therapy in 38 trials, 2.3% of patients developed second primary malignancie...
Nature Medicine, Published online: 20 January 2025; doi:10.1038/s41591-024-03412-wAn atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks of GLP-1RA...
Nature Medicine, Published online: 20 January 2025; doi:10.1038/s41591-024-03341-8A finger-based brain–computer interface was developed for a person with tetraplegia to allow him to fly a virtual quadcopter, an innovation that can lead...