Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03678-8A novel personalized phage therapy strategy that selects phages for a predicted evolutionary trade-off may represent a viable alternative approach for the ...
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03688-6As presented at the 2025 AACR Annual Meeting, in an ongoing first-in-human phase 1 trial of a next-generation KRAS-G12C inhibitor in patients with solid tu...
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03625-7This study identifies a unique multiple sclerosis lesion, the broad rim lesion, which is associated with rapid disease progression and marked by a distinct...
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03653-3Molecular analyses of longitudinal kidney biopsies from a phase 2 trial testing an anti-CD38 antibody for kidney transplant rejection show temporary suppre...
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03687-7The stochasticity of biological aging
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03731-6Author Correction: Autologous T cell therapy for PRAME+ advanced solid tumors in HLA-A*02+ patients: a phase 1 trial
Nature Medicine, Published online: 29 April 2025; doi:10.1038/s41591-025-03668-wSPIRIT 2025 provides updated guidance to authors, reviewers and editors, when preparing clinical trial protocols to enhance their transparency and complete...
Nature Medicine, Published online: 28 April 2025; doi:10.1038/s41591-025-03700-zProteomics analyses of thousands of proteins in human cerebrospinal fluid reveal that the ratio of two proteins can be used to predict future dementia or c...
Nature Medicine, Published online: 28 April 2025; doi:10.1038/s41591-025-03700-zProteomics analyses of thousands of proteins in human cerebrospinal fluid reveal that the ratio of two proteins can be used to predict future dementia or c...
Nature Medicine, Published online: 28 April 2025; doi:10.1038/s41591-025-03629-3Forecast models of bacterial antimicrobial resistance (AMR) surveillance records from 101 countries reveal that the global burden of AMR is associated with...
Nature Medicine, Published online: 28 April 2025; doi:10.1038/d41591-025-00027-7The polygenic score, based on analysis of DNA from a saliva sample, led to the detection of more cancers than would have been found with standard screening...
Nature Medicine, Published online: 25 April 2025; doi:10.1038/s41591-025-03713-8Author Correction: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Nature Medicine, Published online: 25 April 2025; doi:10.1038/s41591-025-03717-4Author Correction: T cell malignancies after CAR T cell therapy in the DESCAR-T registry
Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03726-3The open-source DeepSeek large language model showed variable performance relative to two leading models when benchmarked on four different medical tasks, ...
Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03727-2In an evaluation involving 125 standardized patient cases, open-source DeepSeek large language models are shown to perform at least on par with state-of-th...
Nature Medicine, Published online: 23 April 2025; doi:10.1038/s41591-025-03639-1A trial that used a master randomized design found that the skills commonly found in smartphone-based cognitive behavioral therapy, when tested alone or in...