As of November, 2024, SARS-CoV-2 omicron JN.1 subvariants, such as KP.2 (JN.1.11.1.2),1 KP.3 (JN.1.11.1.3), KP.3.1.1 (JN.1.11.1.3.1.1), and XEC2—a recombinant lineage between KS.1.1 (JN.13.1.1.1) and KP.3.3 (JN.1.11.1.3.3)—have been circulating in seve...
The deployment of the RTS,S/AS01 vaccine and the prequalification of R21/Matrix-M vaccine are important milestones that target child health and survival, especially in Africa.1 Sub-Saharan Africa bears approximately 94% of global malaria cases and deat...
RH5.1/Matrix-M appears safe and highly immunogenic in African children and shows promising efficacy against clinical malaria when given in a delayed third-dose regimen. This trial is ongoing to further monitor efficacy over time.
We read with interest the Correspondence by Concetta Castilletti and colleagues1 on Oropouche virus cases imported into Europe and we agree with the need for accurate identification and timely diagnosis of Oropouche virus cases. Oropouche virus has eme...
The publication of a phase 3 trial by Terry Nolan and colleagues in The Lancet Infectious Diseases marks a key step towards licensing a new GSK vaccine (MenABCWY) which targets five Neisseria meningitidis serogroups.1 The vaccine combines a conjugate v...
This study demonstrates breadth of immune response against a panel of 110 MenB strains for the MenB component of the investigational MenABCWY vaccine, when administered as a 0–6 months schedule to the target population of adolescents and young adults, ...
The Lancet Infectious Diseases. Clinical trials versus the real world in tuberculosis control. Lancet Infect Dis 2024; 24: 1287—In this Editorial, the link for further reading on the trial on 4-month therapy of tuberculosis in San Francisco, CA, USA, s...
Since the COVID-19 pandemic, genomic surveillance for the pneumoviruses human respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) has increased substantially worldwide (appendix). In a recent article in The Lancet Infectious Diseases, Sl...
A HIV programme designed for adolescent girls and young women in sub-Saharan Africa celebrates its tenth anniversary on World AIDS Day this year. Udani Samarasekera reports.
Tuberculosis remains a public health concern, and electronic monitors show promise in improving treatment adherence and health outcomes among patients with tuberculosis. This Review aims to provide a comprehensive understanding of the implementation ba...
The Newsdesk piece “Global upsurge in dengue in 2024”1 highlights the alarming rise in dengue cases globally, with Brazil, the world's hardest-hit country, reporting the largest dengue epidemic in recorded history, with more than 6·5 million confirmed ...
CPA is associated with substantial mortality. Advancing age, CPA subtype, and underlying comorbidities are important predictors of mortality. Future studies should focus on identifying appropriate treatment strategies tailored to different risk groups.
Chronic pulmonary aspergillosis (CPA) is a collection of progressive diseases of the lung caused by infection with members of the Aspergillus genus. The five subtypes of CPA are aspergilloma, Aspergillus nodule(s), chronic cavitary pulmonary aspergillo...
Monkeypox virus (MPXV) causes mpox, a disease largely confined to west and central Africa until 2022, when the global spread of MPXV clade IIb was declared a public health emergency of international concern (PHEIC). Another PHEIC was declared in 2024 f...
In the last twenty years, the WHO public health approach to AIDS has made significant progress around the world. The scale-up of antiretroviral therapy (ART) has meant that ART coverage is currently at 75% and rising to the point where many now believe...
U=Me is the title of a short film of around 28 minutes that can help in disseminating awareness about various aspects of HIV infection, including misconceptions and stigma. Directed by Umesh Vinayak Kulkarni and produced by Sanjay Pujari, the short fil...