Over 80 000 cases of mpox (formerly known as monkeypox) infection have been confirmed since May 2022.1,2 Infection elicits both cell-mediated and humoral immunity.3 Modified Vaccinia Ankara Bavarian Nordic (MVA-BN) vaccine has been used during the outb...
Over 80 000 cases of mpox (formerly known as monkeypox) infection have been confirmed since May 2022.1,2 Infection elicits both cell-mediated and humoral immunity.3 Modified Vaccinia Ankara Bavarian Nordic (MVA-BN) vaccine has been used during the outb...
Since 2022, monkeypox virus (MPXV) has been causing a multinational epidemic with Brazil as one of the most affected countries.1,2 During the current mpox (formally known as monkeypox) epidemic, men with AIDS are at increased risk of severe illness and...
Since 2022, monkeypox virus (MPXV) has been causing a multinational epidemic with Brazil as one of the most affected countries.1,2 During the current mpox (formally known as monkeypox) epidemic, men with AIDS are at increased risk of severe illness and...
As SARS-CoV-2 evolves, emerging variants such as BA.2.86 raise public health concerns and challenge existing control measures due to the potential for increased transmissibility and immune escape.1 By late July, 2023, a number of countries had detected...
Over the past 150 years vaccination regimens for rabies have evolved considerably. Starting from Pasteur's experimental vaccination of Joseph Meister in 1885,1 nerve tissue vaccines that were lifesaving during their time, have since been replaced by sa...
Single intramuscular rabies vaccination can effectively prime travellers (aged 18–50 years), and potentially other populations, and could replace current standard two-visit rabies vaccination as PrEP.
Maranda B, Labbé SM, Lurquin M, et al. Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial. Lancet Infect Dis 2023; published online Aug 21. https://doi.o...
Maranda B, Labbé SM, Lurquin M, et al. Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial. Lancet Infect Dis 2023; published online Aug 21. https://doi.o...
The Grand Round concerns a 24-year-old man from Zimbabwe who was studying and living in Poland. The patient had been complaining of abdominal pain, fatigue, alternating diarrhoea and constipation, and presence of blood in his stool for 3 years. The pat...
The Grand Round concerns a 24-year-old man from Zimbabwe who was studying and living in Poland. The patient had been complaining of abdominal pain, fatigue, alternating diarrhoea and constipation, and presence of blood in his stool for 3 years. The pat...
A 59-year-old treatment-naive patient with advanced HIV infection presented with a severe and protracted course of mpox (formerly known as monkeypox) that did not respond to the current mpox treatment options. The patient worsened clinically, and devel...
A 59-year-old treatment-naive patient with advanced HIV infection presented with a severe and protracted course of mpox (formerly known as monkeypox) that did not respond to the current mpox treatment options. The patient worsened clinically, and devel...
Next-generation sequencing (NGS) of genomic data has established its fundamental value in public health surveillance, research and development, and precision medicine. In Africa, severe shortages of competent experts in genomics and bioinformatics, few...
Next-generation sequencing (NGS) of genomic data has established its fundamental value in public health surveillance, research and development, and precision medicine. In Africa, severe shortages of competent experts in genomics and bioinformatics, few...
Both molnupiravir and ritonavir-boosted nirmatrelvir accelerate oropharyngeal SARS-CoV-2 viral clearance in patients with COVID-19, but the antiviral effect of ritonavir-boosted nirmatrelvir was substantially greater. Measurement of oropharyngeal viral...