WHO now recommends the use of 6–9 month, all-oral regimens for the treatment of multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis.1 Bedaquiline is a key drug in these regimens, and has contributed to substantial improvements in patien...
“Through science and health we build bridges to work together”, explains Khitam Muhsen about the relationship between Israeli Jewish and Arab researchers, as well as with Palestinian researchers trying to improve health for all. Muhsen's belief in this...
“Through science and health we build bridges to work together”, explains Khitam Muhsen about the relationship between Israeli Jewish and Arab researchers, as well as with Palestinian researchers trying to improve health for all. Muhsen's belief in this...
According to data from the UN High Commissioner for Refugees of Mexico, 76 853 people born in Haiti, Honduras, Cuba, and Venezuela requested asylum in Mexico during the first half of 2023.1 Concomitantly, an undetermined number of people without docume...
According to data from the UN High Commissioner for Refugees of Mexico, 76 853 people born in Haiti, Honduras, Cuba, and Venezuela requested asylum in Mexico during the first half of 2023.1 Concomitantly, an undetermined number of people without docume...
Moxidectin was non-inferior to ivermectin in terms of efficacy in the treatment of strongyloidiasis. Additionally, both drugs had a similar safety profile. The fixed dose and lower cost of moxidectin compared with ivermectin make it a valuable alternat...
Strongyloidiasis, caused by Strongyloides stercoralis, remains a neglected tropical parasitic infection despite substantial public health concerns. Currently, the gold-standard strongyloidiasis treatment endorsed by WHO entails a single weight-adjusted...
Strongyloidiasis, caused by Strongyloides stercoralis, remains a neglected tropical parasitic infection despite substantial public health concerns. Currently, the gold-standard strongyloidiasis treatment endorsed by WHO entails a single weight-adjusted...
In late July, 2023, SARS-CoV-2 surveillance programmes identified a new, highly mutated omicron subvariant, BA.2.86.1 Initial estimates place the effective reproduction number of BA.2.86 at 1·29-times greater than that of XBB.1.5 and near equivalent to...
In late July, 2023, SARS-CoV-2 surveillance programmes identified a new, highly mutated omicron subvariant, BA.2.86.1 Initial estimates place the effective reproduction number of BA.2.86 at 1·29-times greater than that of XBB.1.5 and near equivalent to...
Moxidectin was non-inferior to ivermectin in terms of efficacy in the treatment of strongyloidiasis. Additionally, both drugs had a similar safety profile. The fixed dose and lower cost of moxidectin compared with ivermectin make it a valuable alternat...
Although cellular immunity has garnered much attention in the era of single-cell technologies, humoral innate immunity has receded in priority due to its presumed limited roles. Hence, despite the long-recognised bactericidal activity of serum—a functi...
MTB-HR showed promising diagnostic accuracy for culture-confirmed tuberculosis in this large, geographically diverse, paediatric cohort and hard-to-diagnose subgroups.
Each year, an estimated 1·2 million incident cases of tuberculosis occur in children younger than 15 years globally, and approximately a quarter of these children will die from tuberculosis.1 The majority of the childhood tuberculosis cases and deaths ...
The recent understanding that hydrophobic β-lactams have greater affinity for organic anion transporter-3 (OAT-3) of the proximal renal tubule could provide valuable insights for anticipating β-lactams that may exacerbate vancomycin-induced nephrotoxic...
Globally, the number of new HIV infections remains unacceptably high, and urgent new approaches are needed to advance HIV vaccine science. However, the development of a preventive HIV vaccine has proven to be an intractable scientific challenge. Recent...