We have an ethical imperative to learn from recent influenza H1N1 and COVID-19 pandemics to better prepare for the next one. WHO has highlighted the need for surveillance frameworks that can be implemented across states.1 For any future epidemic or pan...
VLA15 was safe, well tolerated, and elicited robust antibody responses to all six OspA serotypes. These findings support further clinical development of VLA15 using the 180 μg dose and 0-2-6-month schedule, which was associated with the greatest immune...
Lyme borreliosis is the most common vector borne infectious disease in North America and Europe and both its incidence and the geographical range of endemic areas are increasing.1–3 Lyme borreliosis is a systemic infectious disease that can affect mult...
Long-acting therapy had non-inferior efficacy compared with oral therapy, with a good safety profile, and can be considered for African treatment programmes.
Cabotegravir and rilpivirine as a complete long-acting injectable regimen is recommended in international guidelines in virologically suppressed adults for maintenance therapy, as an alternative to daily oral therapy.1–3 Most guidelines cite improved q...
Ad26.RSV.preF–RSV preF protein maintained high efficacy against RSV LRTD in older adults across three RSV seasons.
Respiratory syncytial virus (RSV) remains a major cause of life-threatening respiratory illness in older adults. Estimates suggest that more than 30 000 adults older than 60 years die from RSV every year in high-income countries.1 However, after almost...
Doxycycline PEP strongly reduced the incidence of chlamydia and syphilis in MSM, but we did not show efficacy of the 4CmenB vaccine for gonorrhoea. Doxycycline PEP should be assessed in other populations, such as heterosexual men and women, and its eff...
Globally, there are more than 1 million sexually transmitted infections (STIs) acquired every day,1 with men who have sex with men (MSM) and transgender women being disproportionately impacted.2 In the past 5 years, studies have examined the potential ...
Ares-Gómez S, Mallah N, Santiago-Pérez M-I, et al. Effectiveness and impact of universal prophylaxis with nirsevimab in infants against hospitalisation for respiratory syncytial virus in Galicia, Spain: initial results of a population-based longitudina...
Drug-resistant tuberculosis causes 30% of all deaths due to antimicrobial resistance.1 One in three patients do not survive treatment for rifampicin-resistant tuberculosis and most have to pay catastrophic costs for their treatment.2 In 2015, it was pr...
Targeted NGS is highly sensitive and specific for detecting drug resistance across panels of tuberculosis drugs and can be performed directly on clinical samples. There is a paucity of data on performance for some currently recommended drugs. The barri...
Loss is pervasive, and COVID-19 accentuated its inescapable nature. Loss of life, health, economic security, and social well-being affected us all. Loss and trauma in the COVID-19 era is a collection of essays originally published in the Journal of Los...
Cullen Reese's The measle outbreak in Manatee Bay: complete story of the breakout, effective prevention, lessons, challenges, and strategies for healthier communities focuses on a measles outbreak that took place in early 2024 at Manatee Bay Elementary...
Military medicine and the hidden costs of war is the third publication by award winning Professor of Political Science, Tanisha M Fazal. Forming part of Oxford University Press's Bridging The Gap' series, this book is a comprehensive study of how the U...
Sometime around August 2015, health care providers in northeastern Brazil noticed an unusual number of babies born with severe microcephaly. A gynaecologist in a hospital in Campino Grande in Paraíba, for example, who would typically expect to see one ...