The avian influenza A(H5N1) virus was first identified in southern China in 1996, leading to substantial outbreaks among poultry in Hong Kong in 1997, which resulted in 18 human infections. Although the 1997 avian epidemic was controlled, the A(H5N1) v...
Searching for “COVID-19 lessons learned” on PubMed gives you 4840 results—a long list of opinion pieces, reviews, and consensus statements telling us what we can learn from our recent pandemic experience. At the same time, 138 dairy herds in the USA ha...
An outbreak of mpox due to a dangerous new subclade in DR Congo is causing international concern, yet no vaccine is available in the country. Alix Boisson-Walsh reports.
Paireau J, Guillot S, Aït El Belghiti F, et al. Effect of change in vaccine schedule on pertussis epidemiology in France: a modelling and serological study. Lancet Infect Dis 2022; 22: 265–73—The full appendix for this Article has now been supplied. Th...
Transplanting organs from cytomegalovirus-seropositive donors into cytomegalovirus-seronegative recipients is an accepted practice. However, outcomes following transplantation of organs from donors with active cytomegalovirus disease are unknown. We pr...
Chen SC-A, Perfect J, Colombo AL, et al. Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis 2021; 21: e375–86—In figure 5 of this Review, the dose f...
Chen SC-A, Perfect J, Colombo AL, et al. Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis 2021; 21: e375–86—In figure 5 of this Review, the dose f...
Routine surveillance programmes mainly focus on known diseases and clinical syndromes of local importance. However, to be prepared for pathogen X, early detection of unusual illnesses or new pathogens is crucial. With the risk of global spread, timely,...
Routine surveillance programmes mainly focus on known diseases and clinical syndromes of local importance. However, to be prepared for pathogen X, early detection of unusual illnesses or new pathogens is crucial. With the risk of global spread, timely,...
The diagnosis of paediatric tuberculosis remains a challenge due to the non-specificity of symptoms and the paucibacillary nature of tuberculosis in children. However, in the development of new tuberculosis diagnostics, the unique needs of children and...
In 2016, WHO designated Lassa fever a priority disease for epidemic preparedness as part of the WHO Blueprint for Action to Prevent Epidemics. One aspect of preparedness is to promote development of effective medical countermeasures (ie, diagnostics, t...
V116 was non-inferior to PCV20 for the ten serotypes common to both vaccines and superior to PCV20 for all serotypes unique to V116, except for 15C. Immune responses successfully immunobridged between younger and older adults for all serotypes in V116....
Nipah virus causes highly lethal disease, with case-fatality rates ranging from 40% to 100% in recognised outbreaks. No treatments or licensed vaccines are currently available for the prevention and control of Nipah virus infection. In 2019, WHO publis...
Pneumonia causes a considerable burden of disease, especially in adults older than 65 years who have higher rates of related hospital admission and deaths.1 Infections with pneumococcal bacteria are a substantial contributor to the global pneumonia bur...
Doxycycline as a post-exposure prophylaxis (doxy-PEP) reduces rates of bacterial sexually transmitted infections (STIs).1 However, doxy-PEP might select for tetracycline resistance in Neisseria gonorrhoeae and coresistance to other antibiotics, includi...
The SARS-CoV-2 JN.1 variant (BA.2.86.1.1), arising from BA.2.86.1 with spike-protein substitution Leu455Ser, had outcompeted the previously predominant XBB lineages by the beginning of 2024.1 Subsequently, JN.1 subvariants, including KP.2 (JN.1.11.1.2)...