[Correspondence] Tracking the spread of avian influenza A(H5N1) with alternative surveillance methods: the example of wastewater data

Di |2024-08-03T00:30:01+02:00Agosto 3rd, 2024|Categorie: Coronavirus Lancet|

The global health landscape is currently dominated by the threat of avian influenza, a public health challenge of unprecedented magnitude. We are on the brink of a potential crisis, where pandemic risk is severely underestimated and efforts to prepare ...

[Articles] Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan: a randomised, double-blind, phase 2, proof-of-concept superiority trial

Di |2024-08-02T00:30:01+02:00Agosto 2nd, 2024|Categorie: Coronavirus Lancet|

Treatment with either dose of fosravuconazole was not superior to itraconazole, and the two doses had a numerically lower efficacy. However, fosravuconazole presented no new safety signals, and its lower pill burden and reduced risk of drug–drug intera...

[Articles] Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan: a randomised, double-blind, phase 2, proof-of-concept superiority trial

Di |2024-08-02T00:30:01+02:00Agosto 2nd, 2024|Categorie: Coronavirus Lancet|

Treatment with either dose of fosravuconazole was not superior to itraconazole, and the two doses had a numerically lower efficacy. However, fosravuconazole presented no new safety signals, and its lower pill burden and reduced risk of drug–drug intera...

[Articles] Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against Rift Valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial

Di |2024-07-26T00:30:01+02:00Luglio 26th, 2024|Categorie: Coronavirus Lancet|

The hRVFV-4s vaccine showed a high safety profile and excellent tolerability across all tested dose regimens, eliciting robust immune responses, particularly with the high-dose administration. The findings strongly support further clinical development ...

[Correspondence] Mortality of H5N1 human infections might be due to H5N1 virus pneumonia and could decrease by switching receptor

Di |2024-07-25T00:30:02+02:00Luglio 25th, 2024|Categorie: Coronavirus Lancet|

The increasing host range and ability of avian influenza viruses to spread between mammals and humans raises concerns about a potential pandemic risk.1 This pandemic risk is a concern as the mortality was 458 (52%) of the 876 influenza A(H5N1) cases re...

[Correspondence] Mortality of H5N1 human infections might be due to H5N1 virus pneumonia and could decrease by switching receptor

Di |2024-07-25T00:30:02+02:00Luglio 25th, 2024|Categorie: Coronavirus Lancet|

The increasing host range and ability of avian influenza viruses to spread between mammals and humans raises concerns about a potential pandemic risk.1 This pandemic risk is a concern as the mortality was 458 (52%) of the 876 influenza A(H5N1) cases re...

[Correspondence] Recombination as an evolutionary driver of MERS-related coronavirus emergence

Di |2024-07-25T00:30:01+02:00Luglio 25th, 2024|Categorie: Coronavirus Lancet|

In their study, Alimuddin Zumla and colleagues1 highlighted the potential threat of MERS-related coronaviruses (MERSr-CoV, subgenus Merbecovirus) to global health. A key concern is the ability of the virus to use diverse cell entry receptors, including...

[Correspondence] Recombination as an evolutionary driver of MERS-related coronavirus emergence

Di |2024-07-25T00:30:01+02:00Luglio 25th, 2024|Categorie: Coronavirus Lancet|

In their study, Alimuddin Zumla and colleagues1 highlighted the potential threat of MERS-related coronaviruses (MERSr-CoV, subgenus Merbecovirus) to global health. A key concern is the ability of the virus to use diverse cell entry receptors, including...

[Correspondence] Artificial intelligence to transform public health in Africa

Di |2024-07-23T00:30:01+02:00Luglio 23rd, 2024|Categorie: Coronavirus Lancet|

Africa faces numerous health challenges, straining the continent's limited health services. Emerging threats, such as Ebola, mpox, and frequent cholera outbreaks highlight the need for a proactive, coordinated, and unified approach to infectious diseas...

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