People most at risk of severe COVID-19 have been prioritised for both monoclonal antibody (mAb) therapy and vaccination. Although mAbs can provide levels of protection approaching that of vaccination,1 they require repeated administration, and ongoing ...
At the onset of the pandemic, Glenda Gray, Lead Co-Investigator at Sisonke and President of the South African Medical Research Council, did something that she had not done in years: she stopped wearing her watch. March, 2020, marked the beginning of a ...
At the onset of the pandemic, Glenda Gray, Lead Co-Investigator at Sisonke and President of the South African Medical Research Council, did something that she had not done in years: she stopped wearing her watch. March, 2020, marked the beginning of a ...
In the past few months, many authors have reported on an outbreak of a so-called dangerous clade I of mpox circulating mainly in DR Congo, which causes more severe symptoms than clade II that has been prevalent in west Africa, and during the global out...
HIV, gender and the politics of medicine by Elizabeth Mills, Senior Lecturer in International Development at the University of Sussex, Brighton, UK, discusses the ways in which political policy affects HIV treatment. Although Mills has been researching...
Historically, the control of infectious diseases in Sierra Leone has been tied with the transatlantic slave trade, the British resettlement of freed slaves in the eighteenth and nineteenth centuries, and the subsequent colonisation by the British. In A...
McMahon R, Toepfer S, Sattler N, et al. Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA: a single-arm, multicentre, phase 3b study. Lancet Infect Dis 202...
Oropouche virus (OROV) is an orthobunyavirus mainly transmitted by the bites of Culicoides paraensis. OROV is endemic to the north region of Brazil and is also found in other countries, including Peru, Panama, and Trinidad and Tobago.1 OROV is the caus...
Brazil has seen an alarming increase in cases of Oropouche fever, an emerging arboviral disease caused by the Oropouche virus, which has sparked public health concerns due to the first confirmed reports of deaths and vertical transmission. This situati...
As COVID-19 restrictions have eased, the resumption of international travel and sexual interactions at large gatherings have fueled the continued spread of human mpox beyond its endemic regions.1–3 The current global circulation of the clade II variant...
In their recent Article,1 Jean-Michel Molina and colleagues provide not only further evidence of the efficacy of doxycycline post-exposure prophylaxis (PEP) but also novel data showing that doxycycline PEP does not select for methicillin-resistant Stap...
In 2014, WHO declared Nepal polio-free.1 However, recent detections of vaccine-derived poliovirus type-3 (VDPV3) in sewage samples from the Tukucha and Bagmati rivers have raised concerns.2 Similar detections were reported in Israel and Palestine betwe...
The 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo resulted in 3470 reported cases, and to date, remains the second largest Ebola virus disease outbreak in recorded history worldwide.1 Amid this crisis, the deployment of t...
The 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo resulted in 3470 reported cases, and to date, remains the second largest Ebola virus disease outbreak in recorded history worldwide.1 Amid this crisis, the deployment of t...
This analysis is the first to provide estimates of the real-world effectiveness of the rVSV-ZEBOV vaccine against Ebola virus disease, amid the widespread use of the vaccine during a large Ebola virus disease outbreak. Our findings confirm that rVSV-ZE...
This analysis is the first to provide estimates of the real-world effectiveness of the rVSV-ZEBOV vaccine against Ebola virus disease, amid the widespread use of the vaccine during a large Ebola virus disease outbreak. Our findings confirm that rVSV-ZE...