In their recent Article,1 Jean-Michel Molina and colleagues provide not only further evidence of the efficacy of doxycycline post-exposure prophylaxis (PEP) but also novel data showing that doxycycline PEP does not select for methicillin-resistant Stap...
In 2014, WHO declared Nepal polio-free.1 However, recent detections of vaccine-derived poliovirus type-3 (VDPV3) in sewage samples from the Tukucha and Bagmati rivers have raised concerns.2 Similar detections were reported in Israel and Palestine betwe...
The 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo resulted in 3470 reported cases, and to date, remains the second largest Ebola virus disease outbreak in recorded history worldwide.1 Amid this crisis, the deployment of t...
The 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo resulted in 3470 reported cases, and to date, remains the second largest Ebola virus disease outbreak in recorded history worldwide.1 Amid this crisis, the deployment of t...
This analysis is the first to provide estimates of the real-world effectiveness of the rVSV-ZEBOV vaccine against Ebola virus disease, amid the widespread use of the vaccine during a large Ebola virus disease outbreak. Our findings confirm that rVSV-ZE...
This analysis is the first to provide estimates of the real-world effectiveness of the rVSV-ZEBOV vaccine against Ebola virus disease, amid the widespread use of the vaccine during a large Ebola virus disease outbreak. Our findings confirm that rVSV-ZE...
WHO reported that as of the end of June, 2024, the multicountry mpox outbreak had caused a total of 99 176 laboratory-confirmed cases.1 The WHO has proposed developing mpox control and elimination plans from 2024 to 2025 in the Strategic Framework for ...
WHO reported that as of the end of June, 2024, the multicountry mpox outbreak had caused a total of 99 176 laboratory-confirmed cases.1 The WHO has proposed developing mpox control and elimination plans from 2024 to 2025 in the Strategic Framework for ...
The SARS-CoV-2 JN.1 variant (BA.2.86.1.1), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted the previously predominant XBB lineages by the beginning of 2024.1 Subsequently, JN.1 subvariants including KP.2 (JN.1.11.1.2) an...
Mindy Nichols Wendell's book Light and air discusses important issues relating to tuberculosis, such as sanatoria, tuberculosis-associated stigma, and equity in tuberculosis care. In the book, Wendell, a noted author of historical fiction for young peo...
In their book The outbreak atlas, authors Rebecca Katz and Mackenzie S Moore, both affiliated to the Center for Global Health Science & Security, Washington DC, USA, sketch various aspects of disease outbreaks. They also portray fascinating case studie...
This study confirms the presence of ART-R in Tanzania, although artemether–lumefantrine and artesunate–amodiaquine showed high efficacy. A context-specific response strategy and vigilance to detect the reduced efficacy of current antimalarial treatment...
In The Lancet Infectious Diseases, Deus S Ishengoma and colleagues1 confirm Tanzania as the fourth African country—alongside Rwanda, Uganda, and Eritrea—to meet the WHO criteria for falciparum malaria with artemisinin partial resistance (ART-R). This f...
PfSPZ Vaccine was safe and well tolerated in adults in Mali. The 9 × 105 and 1·8 × 106 doses of PfSPZ Vaccine administered as per the 4-week schedule, which incorporated presumptive antimalarial treatment before the first vaccine dose, showed significa...
Pregnant women are among the most susceptible to malaria infection, especially in sub-Saharan Africa where more than 12 million pregnant women are at risk each year.1 Infection in pregnancy can lead to placental malaria, in which red blood cells seques...
vYF has a similar safety and immunogenicity profile to YF-VAX. In general, the vYF 5 Log CCID50 dose appeared to show optimal viraemia, safety, and immunogenicity, and was chosen for subsequent development.