A dengue vaccine that is equally immunogenic and effective against all four viral serotypes would address one of the top-ten public health needs.1,2 In 2015, Dengvaxia (CYD-TDV; Sanofi Pasteur, Paris, France) was licensed, followed by the second vaccin...
A dengue vaccine that is equally immunogenic and effective against all four viral serotypes would address one of the top-ten public health needs.1,2 In 2015, Dengvaxia (CYD-TDV; Sanofi Pasteur, Paris, France) was licensed, followed by the second vaccin...
A single dose of Butantan-DV was generally well tolerated and efficacious against symptomatic VCD (caused by DENV-1 and DENV-2) for a mean of 3·7 years. These findings support the continued development of Butantan-DV to prevent dengue disease in childr...
A single dose of Butantan-DV was generally well tolerated and efficacious against symptomatic VCD (caused by DENV-1 and DENV-2) for a mean of 3·7 years. These findings support the continued development of Butantan-DV to prevent dengue disease in childr...
The global health landscape is currently dominated by the threat of avian influenza, a public health challenge of unprecedented magnitude. We are on the brink of a potential crisis, where pandemic risk is severely underestimated and efforts to prepare ...
The global health landscape is currently dominated by the threat of avian influenza, a public health challenge of unprecedented magnitude. We are on the brink of a potential crisis, where pandemic risk is severely underestimated and efforts to prepare ...
Treatment with either dose of fosravuconazole was not superior to itraconazole, and the two doses had a numerically lower efficacy. However, fosravuconazole presented no new safety signals, and its lower pill burden and reduced risk of drug–drug intera...
Eumycetoma is a chronic and destructive fungal infection that mainly affects the extremities via the development of granulomatous subcutaneous masses.1 Occurring in tropical and subtropical regions, it is most commonly caused by the fungus Madurella my...
Eumycetoma is a chronic and destructive fungal infection that mainly affects the extremities via the development of granulomatous subcutaneous masses.1 Occurring in tropical and subtropical regions, it is most commonly caused by the fungus Madurella my...
Treatment with either dose of fosravuconazole was not superior to itraconazole, and the two doses had a numerically lower efficacy. However, fosravuconazole presented no new safety signals, and its lower pill burden and reduced risk of drug–drug intera...
Toledo ME, Monteagudo Diaz S,Montenegro Calderón T, Kreppel K, Van Damme E, Vanlerberghe V. Preparedness for emerging epidemic threats: detection of Oropouche circulation in Cuba. Lancet Infect Dis 2024; 24: e484—In this Correspondence, Maria Eugenia T...
In On Call: A doctor's journey in public service, Anthony Fauci shares his story on how the Brooklyn boy from modest beginnings became the director of the National Institute of Allergy and Infectious Diseases (NIAID) and ultimately the voice of reason ...
The hRVFV-4s vaccine showed a high safety profile and excellent tolerability across all tested dose regimens, eliciting robust immune responses, particularly with the high-dose administration. The findings strongly support further clinical development ...
Knowledge of classical and next-generation vaccine principles has improved considerably over the past two decades. This expertise has enabled the development of vaccines against various infectious diseases, including principles such as whole inactivate...
The increasing host range and ability of avian influenza viruses to spread between mammals and humans raises concerns about a potential pandemic risk.1 This pandemic risk is a concern as the mortality was 458 (52%) of the 876 influenza A(H5N1) cases re...
The increasing host range and ability of avian influenza viruses to spread between mammals and humans raises concerns about a potential pandemic risk.1 This pandemic risk is a concern as the mortality was 458 (52%) of the 876 influenza A(H5N1) cases re...