The SARS-CoV-2 KP.3.1.1 lineage is currently the dominating lineage on several continents. In parallel, the XEC lineage, a recombinant of KS.1.1 and KP.3.3,1 is rapidly gaining prevalence in Europe and North America, and is on track to become the next ...
Awareness of YEZV infection is important and clinicians should consider the virus when diagnosing patients with suitable symptoms.
Yezo virus is a causative agent of tick-borne febrile illness first recognized in Hokkaido, the northernmost island of Japan, in 2019 (reported in 2021). Yezo virus is a member of the genus Orthonairovirus and family Nairoviridae, and is phylogenetical...
Heil EL, McCreary EK. REVISITing treatment of metallo-β-lactamases. Lancet Infect Dis 2024; published online Oct 7. https://doi.org/10.1016/S1473-3099(24)00561-9—In this Comment, two corrections have been made. The correct treatment difference for clin...
Invasive meningococcal disease continues to be a life-threatening infectious disease with rapid clinical progression and a case-fatality rate of up to 20% in young adults.1 In 2019, an estimated 2·51 million cases of meningitis occurred globally, with ...
NmCV-5 was non-inferior to MenACWY-D in terms of seroresponse and GMTs, was safe, and demonstrated lot-to-lot consistency. NmCV-5 is prequalified by WHO and was rolled out in the African meningitis belt in April, 2024.
The SARS-CoV-2 JN.1 (BA.2.86.1.1) variant, arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted the previously predominant XBB lineages by the beginning of 2024.1 Subsequently, JN.1 subvariants including KP.2 (JN.1.11.1.2) an...
Disease associated with Cladophialophora bantiana infection is uncommon but can be characterised by severe and life-threatening CNS involvement. Diagnosis is challenging due to both the infection's rarity and non-specific clinical presentation, which c...
Disease associated with Cladophialophora bantiana infection is uncommon but can be characterised by severe and life-threatening CNS involvement. Diagnosis is challenging due to both the infection's rarity and non-specific clinical presentation, which c...
Babiker A, Warner S, Li X, et al. Adjunctive linezolid versus clindamycin for toxin inhibition in β-lactam-treated patients with invasive group A streptococcal infections in 195 US hospitals from 2016 to 2021: a retrospective cohort study with target t...
Babiker A, Warner S, Li X, et al. Adjunctive linezolid versus clindamycin for toxin inhibition in β-lactam-treated patients with invasive group A streptococcal infections in 195 US hospitals from 2016 to 2021: a retrospective cohort study with target t...
This multicentre evaluation demonstrates that culture-free tNGS can provide accurate sequencing results for detection and characterisation of drug resistance from Mycobacterium tuberculosis clinical sediment samples for timely, comprehensive profiling ...
The ability to sequence the Mycobacterium tuberculosis genome represents the biggest microbiological advance since Robert Koch identified it as the causative agent of tuberculosis. Routine whole-genome sequencing (WGS) has been implemented in some coun...
In September, 2024, WHO warned of the serious threat of antimicrobial resistance in Ukraine as Russia's invasion continues. Ed Holt reports.
In September, 2024, WHO warned of the serious threat of antimicrobial resistance in Ukraine as Russia's invasion continues. Ed Holt reports.
We read with concern the hepatotoxicity results of the SimpliciTB trial. 11 (7%) of 150 patients treated with bedaquiline, pretomanid, moxifloxacin, and pyrazinamide (BPaMZ) had serious liver toxicity (one patient died of drug-induced liver injury), co...