This study confirms the presence of ART-R in Tanzania, although artemether–lumefantrine and artesunate–amodiaquine showed high efficacy. A context-specific response strategy and vigilance to detect the reduced efficacy of current antimalarial treatment...
In The Lancet Infectious Diseases, Deus S Ishengoma and colleagues1 confirm Tanzania as the fourth African country—alongside Rwanda, Uganda, and Eritrea—to meet the WHO criteria for falciparum malaria with artemisinin partial resistance (ART-R). This f...
PfSPZ Vaccine was safe and well tolerated in adults in Mali. The 9 × 105 and 1·8 × 106 doses of PfSPZ Vaccine administered as per the 4-week schedule, which incorporated presumptive antimalarial treatment before the first vaccine dose, showed significa...
Pregnant women are among the most susceptible to malaria infection, especially in sub-Saharan Africa where more than 12 million pregnant women are at risk each year.1 Infection in pregnancy can lead to placental malaria, in which red blood cells seques...
vYF has a similar safety and immunogenicity profile to YF-VAX. In general, the vYF 5 Log CCID50 dose appeared to show optimal viraemia, safety, and immunogenicity, and was chosen for subsequent development.
In this issue of The Lancet Infectious Diseases, Kayvon Modjarrad and colleagues1 report on the safety and immunogenicity of a next-generation life-attenuated Vero cell line derived yellow fever vaccine, vYF-247. The prospect of a new yellow fever vacc...
Significant reductions in methicillin resistance in S aureus, vancomycin-resistant E faecium, and fluoroquinolone resistance across multiple pathogens suggest that control efforts have had an effect on resistance. The rise in extended-spectrum β-lactam...
Significant reductions in methicillin resistance in S aureus, vancomycin-resistant E faecium, and fluoroquinolone resistance across multiple pathogens suggest that control efforts have had an effect on resistance. The rise in extended-spectrum β-lactam...
Health-care-associated infections (HAIs) are the most frequently occurring adverse events in health care. These infections pose a major threat to patient safety and were regarded as an inevitable risk of health care for many years; however, contemporar...
Health-care-associated infections (HAIs) are the most frequently occurring adverse events in health care. These infections pose a major threat to patient safety and were regarded as an inevitable risk of health care for many years; however, contemporar...
Improving the cleaning and disinfection of shared medical equipment significantly reduced HAIs, underscoring the crucial role of cleaning in improving patient outcomes. Findings emphasise the need for dedicated approaches for cleaning shared equipment.
Improving the cleaning and disinfection of shared medical equipment significantly reduced HAIs, underscoring the crucial role of cleaning in improving patient outcomes. Findings emphasise the need for dedicated approaches for cleaning shared equipment.
Antibiotic resistance is a persistent global health threat.1 Our ability to accurately assess changes in the overall burden of resistant pathogens, the effects of these changes on key clinical outcomes, and the effects of control interventions on antib...
Antibiotic resistance is a persistent global health threat.1 Our ability to accurately assess changes in the overall burden of resistant pathogens, the effects of these changes on key clinical outcomes, and the effects of control interventions on antib...
In their editorial, The Lancet Infectious Diseases editors highlight regarding the uptake of H5N1 influenza A testing on farms that: “Testing is largely voluntary, and uptake has been low, so the true extent of spread is unclear”.1 Farm owners have bee...
In their editorial, The Lancet Infectious Diseases editors highlight regarding the uptake of H5N1 influenza A testing on farms that: “Testing is largely voluntary, and uptake has been low, so the true extent of spread is unclear”.1 Farm owners have bee...