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[Review] Barriers and facilitators to the implementation of electronic monitors to improve adherence and health outcomes in patients with tuberculosis: a systematic review

Di |2024-11-30T00:30:01+01:00Novembre 30th, 2024|Categorie: Coronavirus Lancet|

Tuberculosis remains a public health concern, and electronic monitors show promise in improving treatment adherence and health outcomes among patients with tuberculosis. This Review aims to provide a comprehensive understanding of the implementation ba...

[Review] Representativeness and adverse event reporting in late-phase clinical trials for rifampin-susceptible tuberculosis: a systematic review

Di |2024-11-27T00:30:01+01:00Novembre 27th, 2024|Categorie: Coronavirus Lancet|

We did a systematic review and meta-analysis of trials of treatment for rifampicin-susceptible tuberculosis to evaluate the representativeness of participants compared with characteristics of the global population of people with tuberculosis, and the a...

[Articles] Safety, pharmacokinetics, and early bactericidal activity of quabodepistat in combination with delamanid, bedaquiline, or both in adults with pulmonary tuberculosis: a randomised, active-controlled, open-label trial

Di |2024-11-27T00:30:01+01:00Novembre 27th, 2024|Categorie: Coronavirus Lancet|

In this 14-day trial, quabodepistat plus delamanid plus bedaquiline, a novel three-drug combination, appeared to be safe, well tolerated, and provided robust early bactericidal activity in adults with drug-susceptible pulmonary tuberculosis. Further ev...

[Correspondence] Additional lessons to prepare for rapid research response to possible vertical transmission of Oropouche virus in Brazil

Di |2024-11-26T00:30:03+01:00Novembre 26th, 2024|Categorie: Coronavirus Lancet|

Brazilian researchers published a Correspondence piece listing some “key lessons” learned after the Zika aftermath in Brazil.1 In the last decade, Brazil has been the epicentre of two health emergencies, Zika and COVID-19, with particular consequences ...

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