H3N2 influenza viruses represent serious respiratory pathogens for the elderly because active circulation of H3N2 viruses is associated with an increased risk of hospitalisation and influenza-related mortality in this age group.1 Several antigenic clad...
These data support the continued clinical development of mRNA-based next-generation seasonal influenza vaccines with broadened influenza A/H3N2 strain coverage.
The available evidence for non-ICU CAP and AECOPD supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts of the scientific community should be directed at implementing this evidence in daily practice. Hig...
VLA1553 was generally safe and induced seroprotective titres in almost all vaccinated adolescents with favourable safety data in adolescents who were seropositive at baseline. The data support the use of VLA1553 for the prevention of disease caused by ...
The battle against antimicrobial resistance (AMR) demands critical evaluation of antibiotic treatment protocols, particularly for respiratory tract infections (RTIs). The umbrella review in The Lancet Infectious Diseases by Suzanne M E Kuijpers and col...
Chikungunya virus causes an emerging mosquito-borne viral infection that is endemic to much of Latin America, Africa, and south and southeast Asia. Chikungunya is prone to 8–15 year cycles of temporary epidemic expansion, with the last global outbreak ...
Casirivimab and imdevimab administration before or at the time of COVID-19 vaccination reduced the elicitation of SARS-CoV-2 neutralising antibodies, but minimal effect was observed when vaccination occurred before mAb administration. Although the clin...
Casirivimab and imdevimab administration before or at the time of COVID-19 vaccination reduced the elicitation of SARS-CoV-2 neutralising antibodies, but minimal effect was observed when vaccination occurred before mAb administration. Although the clin...
Monkeypox virus (MPXV) is a zoonotic virus and the causative agent of mpox (formerly known as monkeypox) disease1 previously limited to countries, such as Nigeria and the Democratic Republic of the Congo, except for occasional importations globally. Ho...
Monkeypox virus (MPXV) is a zoonotic virus and the causative agent of mpox (formerly known as monkeypox) disease1 previously limited to countries, such as Nigeria and the Democratic Republic of the Congo, except for occasional importations globally. Ho...
People most at risk of severe COVID-19 have been prioritised for both monoclonal antibody (mAb) therapy and vaccination. Although mAbs can provide levels of protection approaching that of vaccination,1 they require repeated administration, and ongoing ...
People most at risk of severe COVID-19 have been prioritised for both monoclonal antibody (mAb) therapy and vaccination. Although mAbs can provide levels of protection approaching that of vaccination,1 they require repeated administration, and ongoing ...
At the onset of the pandemic, Glenda Gray, Lead Co-Investigator at Sisonke and President of the South African Medical Research Council, did something that she had not done in years: she stopped wearing her watch. March, 2020, marked the beginning of a ...
At the onset of the pandemic, Glenda Gray, Lead Co-Investigator at Sisonke and President of the South African Medical Research Council, did something that she had not done in years: she stopped wearing her watch. March, 2020, marked the beginning of a ...
In the past few months, many authors have reported on an outbreak of a so-called dangerous clade I of mpox circulating mainly in DR Congo, which causes more severe symptoms than clade II that has been prevalent in west Africa, and during the global out...
Historically, the control of infectious diseases in Sierra Leone has been tied with the transatlantic slave trade, the British resettlement of freed slaves in the eighteenth and nineteenth centuries, and the subsequent colonisation by the British. In A...