Boss scarcerati, Massimo Giletti legge il lungo elenco
https://www.youtube.com/watch?v=m5DTYN54Asw
https://www.youtube.com/watch?v=m5DTYN54Asw
BACKGROUND: Phospho-Akt1 (pAkt1) undergoes prolyl hydroxylation at Pro125 and Pro313 by the prolyl hydroxylase-2 (PHD2) in a reaction decarboxylating α-ketoglutarate (αKG). We investigated whether the αKG supplementation could inhibit Akt-mediated activation of platelets and monocytes, in vitro as well as in vivo, by augmenting PHD2 activity.