Computational simulations to dissect the cell immune response dynamics for severe and critical cases of SARS-CoV-2 infection

Di |2021-10-05T13:00:00+02:00Ottobre 5th, 2021|Categorie: Coronavirus PubMed|

CONCLUSIONS: Our computational results highlight that a low viral clearance rate by CD8^(+) T cells could lead to the severity of the disease. This deregulated clearance suggests that it is necessary immunomodulatory strategies during the course of the infection to avoid critical states in COVID-19 patients.

Computational simulations to dissect the cell immune response dynamics for severe and critical cases of SARS-CoV-2 infection

Di |2021-10-05T13:00:00+02:00Ottobre 5th, 2021|Categorie: Coronavirus, Coronavirus PubMed|

CONCLUSIONS: Our computational results highlight that a low viral clearance rate by CD8^(+) T cells could lead to the severity of the disease. This deregulated clearance suggests that it is necessary immunomodulatory strategies during the course of the infection to avoid critical states in COVID-19 patients.